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Porcine models of digestive disease: the future of large animal translational research

Abstract Background/Objectives: Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) effectively manage type 2 diabetes mellitus (T2DM) but may impair gastrointestinal motility, increasing the risk of small intestinal bacterial overgrowth (SIBO)

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Its clinical development was discontinued, and it is sold only as a research chemical labeled for laboratory use

VEGF drives angiogenesis the formation of new blood vessels which directly improves the delivery of oxygen and nutrients to the follicle's dermal papilla cells

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