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Integrating UGT inhibition data into the rule-of-two model significantly enhances the prediction accuracy for drug-induced liver injury (DILI) (119)
doi: 10.3390/jcm11164742 45
I feel like it's kind of grainy
At the growth-factor level, BPC-157 modulates expression of EGF (epidermal growth factor), FGF (fibroblast growth factor), and TGF-beta in injured tissue, coordinating a multi-pathway repair response that few single-agent peptides can match
Sources: Sebecic B, Nikolic V, Sikiric P, et al
Immune cells swarm in: neutrophils gobble up debris, while macrophages release cytokines like TNF- and IL-1 to amplify the alarm
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