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doi: 10.3389/fmicb.2022.773238 178 de FariaIJSAguiarERGROlmoRPAlves da SilvaJADaefflerLCarthewRWet al

Impaired adenosine monophosphate-activated protein kinase signalling in dorsal root ganglia neurons is linked to mitochondrial dysfunction and peripheral neuropathy in diabetes

Studies demonstrate that glutathione prevents hydrogen peroxide-induced apoptosis by rescuing mitochondrial membrane potential and blocking ROS accumulation, with protection dependent on HO-1 activation

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Figure 7 displays the LVs that showed significant concentration- and time-dependent responses after benchmark chemical exposure relative to the vehicle control