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After 5 days of treatment, rats treated with MK-801, semaglutide or GLP-1MK-801 had significantly decreased body weight compared with the vehicle-treated rats

Most patients notice cravings, snacking and food noise drop within days of starting

Key Takeaways GLP-1 nausea is common but manageable with the right strategies

But almost no one is talking about the day-to-day realities of living well while using these medications, things like how do you structure meals when your appetite is low, how do you make sure youre getting enough protein

Monounsaturated, polyunsaturated and short-chain fatty acids also stimulate GLP-1 production and receptor activation

doi: 10.1016/S0140-6736(21)01324-6 71 FrasJPDaviesMJRosenstockJPrez ManghiFCFernndez LandLBergmanBKet al