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doi: 10.1039/C8FO01352G

Surprisingly, given the limited amount of training data, we found that an ensemble of multi-task convolutional neural-network (CNN) models that simultaneously predict potency at both GCGR and GLP-1R provides significantly better performance against GLP-1R, whereas performance differences against GCGR were largely not significant

While this has not been proven to happen with Paxlovid, its something researchers are studying closely