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Under-hydrating leads to worse GI symptoms, headaches, kidney stress, and reduced creatine effectiveness

This should help plan the need for interventions more accurately, Grossman says

doi: 10.1073/pnas.1103746108 [DOI] [PMC free article] [PubMed] [Google Scholar] 131.Ramirez-Jarquin UN, Shahani N, Pryor W, et al

general population, the estimated background risk of major birth defect and miscarriage in clinically recognized pregnancies is 2 to 4% and 15 to 20%, respectively

Key Takeaways After reviewing the baseline data, here is what stands out: Weight is the biggest controllable variable

The primary difference lies in administration