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An in vitro study found that prolonged oven heating or boiling (i.e., six minutes or longer) suppressed the inhibitory effect of uncrushed and crushed garlic on platelet aggregation, but crushed garlic retained more anti-aggregatory activity compared to uncrushed garlic (136)

This occurs via the carnitine palmitoyltransferase (CPT) system, with CPT1 aiding the transport of fatty acids into the mitochondria and CPT2 facilitating their release once processed