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A study by Soraya, S., Mahdavi, M., Saeidi, M
Psychological symptoms (especially cravings, depression, and sleep disruption) can persist for weeks or months
In 2008 it has been reported a decreased pituitary responsiveness and an increased adrenal cortisol response in two groups of patients with opioid dependence treated with benzodiazepines and clonidine (30 patients), or with methadone (30 patients)
Experimental observations indicate that DSIP may influence slow-wave sleep dynamics and sleep onset latency, making it a useful tool for investigating mechanisms underlying restorative sleep phases [1]
2003 Feb;24(2):307311
For DSIP alone, we spent several days exploring the literature to pinpoint the peptides most conclusive therapeutic uses and the studies supporting its use toward those ends
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