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In response to the muscle damage and supplementation, circulating levels of free iron (that could possibly react to form hydroxyl radicals) were increased, lactate dehydrogenase and creatine kinase, markers of protein breakdown and damage, were elevated in the supplemented group as well as an increase in markers for oxidative stress

Figure 4 Similarly, combining TLR4/NF-B and Nrf2-ARE pathway modulation offers a comprehensive approach to managing IBD by simultaneously reducing inflammation and enhancing antioxidant defenses

Kang DE, Sur RL, Haleblian GE, Fitzsimons NJ, Borawski KM, Preminger GM

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