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Sample size was determined based on practical considerations, prior experience with similar phase 1 study designs, and the objective of obtaining sufficient safety and pharmacokinetic data to support dose escalation decisions

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(You can search the NIHR 'Be Part of Research' website, but always discuss eligibility with your clinician) What are the established treatment options that might better address my symptoms

Safety and efficacy of exenatide once weekly plus dapagliflozin once daily versus exenatide or dapagliflozin alone in patients with type 2 diabetes inadequately controlled with metformin monotherapy: 52-week results of the DURATION-8 randomized controlled trial