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Furthermore, GLP-1RAs can counteract the diabetes-induced downregulation of the glutamate-aspartate transporter (GLAST), a key glial transporter responsible for clearing extracellular glutamate [57]

It helps reduce appetite and support calorie control

Li M, Li C, Parkhouse WS: Age-related differences in the des IGF-I-mediated activation of Akt-1 and p70 S6K in mouse skeletal muscle

They can yield 1520% weight reductions in adults, previously only possible after bariatric surgery (Gross)

10.1038/s41398-019-0653-9 256 LeclercqS.ForsytheP.BienenstockJ