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They are also present in various brain regions, including areas involved in mood regulation, reward processing, and emotional behaviour
On the flip side, rapid or extreme weight loss can throw off your cycle and make it harder to conceive as your body readjusts
Other therapies were linked to increased adverse events such as stroke [11], hyperkalemia [13,15], hypotension [13], acute kidney injury (AKI) [15], and major adverse cardiovascular events (MACE) [14]
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More serious but less common adverse effects observed in trials or associated with this drug class include: Increased heart rate , a class effect seen with GLP-1 receptor agonists [15] [12] Gallbladder disease , including gallstones (cholelithiasis), which has been associated with rapid weight loss and incretin-based therapies more broadly