Both compounded and FDA-approved branded medications like Ozempic are available
Only tirzepatide is FDA-approved for sleep apnea approved in 2024 for moderate-to-severe obstructive sleep apnea in adults with obesity, the first medication ever FDA-approved for OSA
In addition to the studies demonstrating the central effects of GLP-1 and its analogs on satiety and reduction of energy intake, there are studies showing other central effects of GLP-1 involving BAT
Hyperglycemic crises and related neurological sequelae including seizures and altered consciousness may link to suboptimal glycemic control during GLP-1 RA therapy
Wang X, Li Q, Liu Y, Jiang H, Chen W (2021) Intermittent fasting versus continuous energy-restricted diet for patients with type 2 diabetes mellitus and metabolic syndrome for glycemic control: a systematic review and meta-analysis of randomized controlled trials
Counsel patients regarding the potential risk for MTC with the use of Ozempic and inform them of symptoms of thyroid tumors (e.g., a mass in the neck, dysphagia, dyspnea, persistent hoarseness)