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Facial cream containing GHK-Cu and melatonin increased collagen in photoaged skin of 20 female volunteers, performing better than vitamin C and retinoic acid

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Compressive forces cause increased loading on the AF, generating a concave bending load on the EPs

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Implications for dosing frequency Despite the short serum half-life, daily (rather than multiple-times-daily) dosing has been shown adequate in most BPC-157 rodent studies