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Good discussion here: 2 Likes AustraliaLongevity November 7, 2025, 10:36pm #37 Might incorporate it into my next cut to speed things up

Because not all systemically administered endogenously occurring neurosteroids readily cross the BBB and because these compounds can be metabolized to hormonally active steroids with different mechanisms of action, the therapeutic potential of these compounds is limited

Longer acting GLP-1 receptor agonists and the potential for improved cardiovascular outcomes: a review of current literature

Increased NAD levels: Cellular studies show that 5-Amino-1MQ increases NAD concentrations, which improves mitochondrial function and cellular energy efficiency

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We can use an estimate of 15% body weight loss over the course of 12 months as a foundation for some simple calculations