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The animals were fed standard chow for 1 week in a suitable experimental environment with a 12-h/12-h light/dark cycle and a controlled temperature (25C 1C) and humidity (50 10%)

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Smoking has also been identified as a risk factor for hypothyroidism, but the reason for the association is unknown (34)

Global incidence, prevalence, years lived with disability (YLDs), disability-adjusted life-years (DALYs), and healthy life expectancy (HALE) for 371 diseases and injuries in 204 countries and territories and 811 subnational locations, 19902021: a systematic analysis for the global burden of Disease Study 2021

Per week: 14 swabs (2/day) 4 weeks: 56 swabs recommend 1 100-count box 6 weeks: 84 swabs recommend 1 100-count box 8 weeks: 112 swabs recommend 2 100-count boxes Protocol Overview Concise summary of the once-daily regimen

doi: 10.1186/s12915-022-01497-8