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What clinical evidence supports GLP-1 use in Prader-Willi syndrome

In addition, we used protein immunoprecipitation to verify the interaction between GLP-1R and the PKA/CREB pathway

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doi: 10.9755/ejfa.2019.v31.i11.2025 60

Insulins lead to marked HbA 1c reductions and have a lower risk of GI effects but can lead to weight gain and are generally associated with a higher risk of hypoglycaemia than GLP-1RAs, which would present significant occupational implications for this patient

Sex and Gender Differences in Obesity: Biological, Sociocultural, and Clinical Perspectives Martins, F.O., et al