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Progress in vesicular formulations, including ultra-deformable liposomes (transfersomes and ethosomes), has enhanced skin permeability by allowing the vesicles to go across intercellular routes in the stratum corneum under osmotic gradients or ethanol-induced lipid fluidisation [258, 281]

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resistant spots to pico), the pigmentation depth (epidermal vs dermal different wavelengths), and the Fitzpatrick grade (IV-VI requires 1064nm to avoid PIH

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Grntvedt GR, Sando SB, Lauridsen C, Brthen G, White LR, Salvesen , Aarsland D, Hessen E, Fladby T, Waterloo K, Scheffler K (2022) Association of Klotho protein levels and KL-VS heterozygosity with Alzheimer disease and amyloid and Tau burden