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Also our data confirmed the anti-inflammatory and antioxidant properties of vitamin c as the UTI + C, and UTI + N + C groups showed significant decreases in the inflammatory mediators (MDA, and NFkB) but increases in antioxidants (GSH, and TAC) compared to the UTI group

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Our animal models, induced using endothelin-1 (ET-1), reflect clinically relevant cerebral I/R conditions yet may not fully capture the complexity of human pathophysiology, including inter-individual anatomical variation and comorbidities ( in vivo , including their potential off-target effects and clearance pathways

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Tirzepatide associated with reduced albuminuria in participants with type 2 diabetes: pooled post hoc analysis from the randomized active- and placebo-controlled SURPASS-1-5 clinical trials