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It disrupts the balance of the tumor immune microenvironment by synergistically regulating immune cells, precisely antioxidant, and relieving immune suppression, forming a microenvironment conducive to anti-tumor immunity, thereby exerting a powerful cancer immunotherapy effect and showing good biocompatibility and tumor accumulation characteristics [427, 428]

For resistant or recurring melasma, dermatologists suggest pairing oral glutathione with a topical or cosmetic treatment, such as a chemical peel or microneedling

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The longer needles create more significant micro-injury requiring extended recovery