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Lastly, while no significant changes were observed in CD3+ or CD8+ cells, RETA significantly increased PD-1 mean fluorescent intensity (MFI) in CD8+ T cells compared to Veh, suggesting elevated activation of cytotoxic T cells (Fig

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In addition, the peptide was designed to selectively stimulate GH production in the anterior pituitary without affecting the production of other hormones, such as prolactin and ACTH, which are commonly triggered by other, less selective GHSs [8]