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The article offers this as a proposed explanation rather than a settled finding

By shielding the mitochondria from this specific type of damage, NAC helps to restore efficient aerobic metabolism, thereby reducing the buildup of fatigue-inducing lactate in the brain and peripheral muscles

R.LewisB.OslicaR.FrancisW.et al (2021)

Minerals aid in enzymatic activity, insulin receptor function, redox balance, and steroidogenic regulation, whereas vitamins mainly serve as antioxidants and enzymatic cofactors

Vitamin A in excess also causes serious damage (liver cell damage, hair loss, teratogenic effect during pregnancy)