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Study author Steven Luo, from the School of Clinical Medicine and Trinity College, said: When stopping weight-loss drugs, doctors and patients should be aware of the potential for weight regain and consider ways to mitigate this risk

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This is an actively evolving area of research, but the early results are promising enough to change clinical practice

Moreover, it remains elusive why OTA causes cytotoxicity specifically in the pericentral lobular zone that also expresses much higher levels of CYPs than the midzonal and periportal lobular regions (Ghallab et al

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