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First: what peptides are actually doing The easiest way to think about peptides is this: They are signaling molecules

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Implications for Treatment Persistence and Outcomes Taken together, discontinuations and interruptions in GLP-1RA use were common in this cohort, particularly during the first year of treatment

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Main results HbA1c, body weight, and FPG SGLT2i compared to placebo Four RCTs were included, with a total of 626 patients (304 in the SGLT2i group and 322 in the placebo group), which compared the changes in both HbA1c and body weight among patients with T2DM and low cardiovascular disease risk, from baseline to follow-up ( 2 = 0%) ( Figure 2A ) and body weight levels with low heterogeneity (MD: -1.32, 95% CI: -1.82, -0.82