The hormone also slows down gastric emptying and digestion, which helps us feel physically fuller for longer periods of time. Delayed stomach emptying also prevents blood glucose spikes, per the Cleveland Clinic
E., Hayes, M
Animal studies have also reported elevated resting energy expenditure
Endogenously, GLP-1 is secreted by intestinal L cells in response to food, and has multiple roles: enhancing insulin secretion (in a glucose-dependent way), reducing glucagon secretion, slowing gastric emptying, increasing feelings of fullness/satiety, and improving glucose disposal in peripheral tissues
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Many GLP-1 boosting supplements contain prebiotic fiber that promotes SCFA production (like butyrate), which can stimulate GLP-1 release in the colon