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By curbing oxidative stress and inflammatory responses, GLP-1 RAs can help protect kidney cells from damage, making these drugs particularly useful for diabetic patients with AKD
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Given existing evidence, triple combination therapy can be expected to provide additional cardiorenal protection, although further randomized controlled trials are needed to determine whether triple combination therapy actually has additive or synergetic effects compared with mono or dual therapy
The maintenance of nitrogen balance depends significantly on this role during times of metabolic stress
Therefore, the ratio between reduced and oxidized forms of GSH is an important indicator of the redox environment and, at the same time, contributes to the accomplishment of the molecular mechanisms underlying cell proliferation, differentiation or death in the form of apoptosis (Dickinson and Forman, 2002)
[Accessed on September 9, 2011]
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