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Introduction Interstitial cystitis/bladder pain syndrome (IC/BPS) is a heterogeneous and symptom-based condition marked by bladder or urethral pain and associated lower urinary tract symptoms, especially urinary frequency and urgency, in the absence of infection and other demonstrated pathology

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Proceedings of the National Academy of Sciences 115(8):E1876-E1885. [doi.org]

In a study on renal cancer, fluvastatin inhibited renal cancer cells time- and dose-dependently by induction of cell cycle arrest and apoptosis in the cells

However, the exact role of GST enzymes in the mechanism of ISR is still far from elucidated because transgenic plants overexpressing or suppressing the symbiont-inducible GSTs have been rarely studied (Kao et al., 2016)

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