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2) Treatment with AOD9604 has been found to increase expression of beta-3-AR RNA, indicating that the compound has the potential to enhance lipolytic sensitivity

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10.1164/rccm.200511-1808OC 9 BalsR.WangX.WuZ.FreemanT.BafnaV.ZasloffM.et al (1998)

The Phase 2 readout established the dose-response signal that the Phase 3 program later confirmed at scale

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