MOFA+: a statistical framework for comprehensive integration of multi-modal single-cell data
Nat Rev Neurosci 16:305312
Symptoms Dry mouth on a GLP-1: why it happens and how to ease it July 12, 2026 2 min read The short answer Dry mouth on a GLP-1 usually traces to reduced fluid intake and mild dehydration (quieter thirst, less food-borne water, fluid-draining side effects), not a direct drying of the salivary glands
Note: Always consult with your licensed healthcare provider before making significant changes to your diet or starting a new medication program
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You should avoid Contrave if you: Have a history of seizures, since bupropion can lower the seizure threshold Are dependent on opioids or in opioid withdrawal, as the naltrexone component can trigger withdrawal symptoms Have uncontrolled high blood pressure, because bupropion can further increase blood pressure Have or have had an eating disorder like bulimia or anorexia Are taking monoamine oxidase inhibitors (MAOIs), or have used them in the last 14 days Have severe liver or kidney disease, which may impair how your body processes the medication Have a history of bipolar disorder, since bupropion may trigger manic episodes Are pregnant or breastfeeding Before starting either of these medications, its important to talk to your doctor about your medical history
