glutathione mitochondrial disease

glutathione mitochondrial disease Frontiers Role of Mitochondria in Ferroptosis:

Name: glutathione mitochondrial disease Frontiers Role of Mitochondria in Ferroptosis:
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Description

Scientific Reports 3 , 3263 (2013)

The nanoreactors can catalyze the oxidation of glutathione (GSH) to glutathione disulfide (GSSG) in hypoxic cancer cells

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Dihydroorotate dehydrogenase (DHODH) and mitochondrial GPX4 are responsible for converting CoQ10 to ubiquinol and detoxifying lipid peroxide within mitochondria, thereby contributing to the regulation of ferroptosis [136]