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[DOI] [PMC free article] [PubMed] [Google Scholar] 19.International Conference on Harmonisation of Technical Requirements for Registration of Pharmaceuticals for Human Use ICH Harmonised Tripartite Guideline for Good Clinical Practice E6 (R1)

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Healthy cells have a GSH/GSSG ratio above 100 at rest, while cells exposed to oxidative stress have a ratio between 1 and 10

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Research has demonstrated that L -arginine plays significant roles in various physiological processes, metabolism, and antioxidant defense mechanisms (Wu et al., 2009

doi:10.1016/j.cmet.2015.09.026 85