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Recently, a seventh trial, PIONEER 6 showed noninferiority of oral semaglutide compared with placebo for 3P-MACE among 3,183 T2DM patients, 85% of whom had established CVD, followed for a median of approximately 1.3 years (59)

Furthermore, long-term fracture risk, bone microarchitecture changes, and implant survival in GLP-1 agonist users remain poorly studied

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HRT operates upstream, restoring the hormonal signaling that menopause withdraws

Depending on their sequence and composition, certain peptides may help prevent blood clots, boost the immune system, protect cells against damage, and reduce cholesterol, inflammation, and blood pressure