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The glutathione redox couple (GSH/GSSG) functions together with other redox-active couples, such as NADPH/NADP + and TRX-SH/TRX-SS, to maintain cellular redox homeostasis and propagate redox signals (Foyer and Noctor, 2011

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In a comprehensive clinical overview, researchers explain that this buffering system prevents the toxic accumulation of unoxidized, short-chain acyl groups within the mitochondria

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However, there is a wide variation in glutathione levels among individuals, and there arent established reference ranges