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During the evolution of Cyanobacteria and Proteobacteria, GSH-dependent ROS detoxification systems incorporated enzymes that play crucial roles in these mechanisms and use GSH as a cofactor, such as GSH peroxidases, GSH reductases, glutaredoxins, and GSH-S-transferases [41]

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"Our findings should be viewed as being significant but tentative, as future studies are needed to examine these questions in a much larger and more diverse population," Dr