In the REDEFINE 1 phase 3 trial, cagrilintide 2.4 mg monotherapy produced an average body weight reduction of 11.8% over 68 weeks
This research is especially useful because it helps clarify how amylin-pathway activation influences feeding circuits and neuroendocrine communication between the gut, circulation, and brain
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Lancet 376(9742):687697 Hurvitz SA et al (2018) Neoadjuvant trastuzumab, pertuzumab, and chemotherapy versus trastuzumab emtansine plus pertuzumab in patients with HER2-positive breast cancer (KRISTINE): a randomised, open-label, multicentre, phase 3 trial
In Lee Goldman, Andrew I
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