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(ii) Stratification and Long-term Follow-up of Maternal-Fetal Outcomes: Short-term outcomes (miscarriage, preterm birth, structural malformations, placental complications, fetal growth abnormalities) and mid-to-long-term outcomes (offspring growth trajectories, metabolic phenotypes) must be pre-defined within a standardized follow-up framework to assess potential metabolic programming risks

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10.1111/jth.14234 96 ZhuY.JamesonE.CrosattiM.SchaferH.RajakumarK.BuggT

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When to Contact Your Provider and Safety Considerations Constipation lasting more than 35 days despite home interventions, or accompanied by severe abdominal pain, distension, or loss of appetite, warrants immediate provider contact