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These systems enhance bioavailability through solubility modulation, supersaturation generation via spring and parachute effects, simultaneous improvements in solubility and permeability, and protection of chemical stability (236)

GHK-Cu: Enhances angiogenesis (new blood vessel formation), reduces inflammation, and strengthens skin repair mechanisms

It is currently being investigated in a phase III, multi-center, double-blind, randomized clinical trial for TBI (Cekic and Stein, 2010)