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It plays a vital role in protecting cells from oxidative stress, which occurs when there is an imbalance between free radicals and antioxidants
While dexamethasone only modestly reduced synovial inflammation, it failed to prevent cartilage deterioration, whereas liraglutide significantly enhanced pain thresholds, lowered synovial scores, and preserved cartilage integrity, with 60 g doses notably reducing overall joint damage [140]
Indeed, our previous findings revealed that silencing CDCA7 , a gene overexpressed in lymphoid tumors, specifically inhibited cell growth in 3D gels, without inhibiting proliferation in 2D conditions, and reduced lymphoma growth in vivo and tumor cell migration and invasion [32, 37]
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