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The role of xanthine in resistance development is still not understood and more studies are needed to understand its role and the pathways associated with it, as it may be a potential marker for treatment resistance in different cancers, especially breast cancer

This proactive approach prevents the dangerous combination of severe restriction followed by reactive overeating that characterizes yo-yo dieting patterns

The animals were kept in a controlled environment with stable temperature and humidity under a 12-hour light/dark cycle

These agents have both hormonal and brain targets

This is especially useful for those who clench their jaws at night or during times of stress

In an in vivo study, the cyclophosphamide-induced ICmodel was developed in female rats