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In animal models, acetyl-l-carnitine improved several aspects of diabetic neuropathy [57,58,59,60,61,62,63]

It acts by removing harmful oxygen-containing molecules, which include peroxide and superoxide anions

Nature 590 , 386388 (2021)

While activated CD4 + helper T cell 1 (Th1) cells fight cancer by secreting interferon- (IFN-) to activate macrophages and natural killer (NK) T cells, activated CD8 + T cells have direct cytotoxic effects against tumors [57] (Fig

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