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doi: 10.3389/fphys.2020.567796 Received 30 May 2020 Accepted 22 September 2020 Published 15 October 2020 Volume 11 - 2020 Edited by Olga Sosnovtseva, University of Copenhagen, Denmark Reviewed by Andras Eke, Semmelweis University, Hungary

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HZ: Writing review & editing

Are There Risks or Side Effects

B12 supplements come in several forms: Cyanocobalamin: Widely available and stable Methylcobalamin: Active form often used for nervous system support Hydroxocobalamin: Preferred in some cases for slower release Choosing the right form is especially important for patients with histamine intolerance, as tolerance varies