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The ARRIVE 2.0 checklist (Animal Research: Reporting of In Vivo Experiments) has become standard for any publication and covers 21 items (design, sample size, randomisation, blinding, statistics, ethics)
Brecka repeatedly emphasizes that it should be approached carefully and ideally under medical guidance
With how little we know about the experimental compound, its long term effects, potential negative side effects, etc., I do think it would be irresponsible to recommend it to others, especially athletes one is coaching
It is trait and pathway education, not a drug-response test, and it does not predict response to any specific compound
Development of a self-assembled nanoparticle formulation of orlistat, Nano-ORL, with increased cytotoxicity against human tumor cell lines
doi: 10.1371/journal.pone.0272593
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