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These measures are summarized here for the busy clinician, as are highly valuable diagnostic modalities that have emerged in the last decade, such as high resolution ultrasound (done in-office in many rheumatology practices) and dual-energy computed tomography (DECT) imaging

Angiogenesis & Vascularity: Studied in relation to new blood vessel formation (angiogenesis) and vascular endothelial growth factors, essential for nutrient delivery to damaged tissues

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The RICE protocol (rest, ice, compression, elevation) remains appropriate initial management, with BPC-157 administration added to enhance the subsequent repair phase

Others support renewal

doi: 10.1186/s12943-019-1127-7 5 GonneaudAGagnJMTurgeonNAsselinC