Ongoing research focuses on refining these approaches, improving selectivity, and combining therapies to overcome resistance and enhance efficacy
Abbreviations ASC: Apoptosis speck-like protein -SMA: -smooth muscle actin BLM: Bleomycin ECM: Excessive extracellular matrix F-6-P: Fructose-6-phosphate F-1, 6-BP: Fructose-1, 6-bisphosphate F-2, 6-BP: Fructose-2, 6-bisphosphate Fn: Fibronectin GLP-1R: Glucagon-like peptide-1 receptor GSDMD: Gasdermin D IPF: Idiopathic pulmonary fibrosis IL-18: Interleukin 18 IL-1: Interleukin 1 NLRP3: Nucleotide-binding and oligomerization domain, leucine-rich repeat, and pyrin domain-containing 3 Pan-Kla: Pan-histone lysine lactylation PFK1: 6-phosphofructo-1-kinase PFKFB3: 6-phosphofructo-2-kinase/fructose-2, 6-biphosphatase 3 TNF-: Tumor necrosis factor TGF-1: Transforming growth factor 1 References Perrot CY, Karampitsakos T, Herazo-Maya JD
[DOI] [PubMed] [Google Scholar] 95.Guo Z, Lin J, Sun K, Guo J, Yao X, Wang G, Hou L, Xu J, Guo J, Guo F
On the contrary, the stable clone and wild type did not show any significant difference in their susceptibility towards doxorubicin (3 g/ml)- or radiation (0.21 Gy)-induced cell death
Sterne JAC, Savovi J, Page MJ, Elbers RG, Blencowe NS, Boutron I, Cates CJ, Cheng H, Corbett MS, Eldridge SM, Emberson JR, Hernn MA, Hopewell S, Hrbjartsson A, Junqueira DR, Jni P, Kirkham JJ, Lasserson T, Li T, McAleenan A, Reeves BC, Shepperd S, Shrier I, Stewart LA, Tilling K, White IR, Whiting PF, Higgins JPT
Graves disease: can it be cured
