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L-carnitine and acetyl-L-carnitine enhance mitochondrial activity and energy metabolism by restoring the NAD(H)/NADP(H) ratio, thereby mitigating ROS-induced damage
The ratio and concentrations of L-carnitine and its acyl derivatives serve as biomarkers for mitochondrial metabolism , fatty acid oxidation defects, and metabolic stress
Funding The present study was supported by the National Natural Science Foundation of China (82422003), Huazhong University of Science and Technology Fundamental Research Program, the Tongji Hospital (HUST) Foundation for Excellent Young Scientists and, Hubei Provincial Medical Youth Elite Talent Program (SCZ202412), the Tongji Hospital (HUST) Cultivation Program (2024B35)
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