Consequently, CHAC1s function in NSCLC highlights its dual role in supporting cellular metabolism and contributing to the vulnerability of cancer cells to ferroptosis (Ward et al., 2024)
Yi et al found that TMAO aggravated high glucose-induced pyroptosis in human renal proximal tubular epithelial cells
Emma F, Hoff WV, Hohenfellner K, Topaloglu R, Greco M, Ariceta G, Bettini C, Bockenhauer D, Veys K, Pape L, Hulton S, Collin S, Ozaltin F, Servais A, Deschenes G, Novo R, Bertholet-Thomas A, Oh J, Cornelissen E, Janssen M, Haffner D, Rava L, Antignac C, Devuyst O, Niaudet P, Levtchenko E (2021) An international cohort study spanning five decades assessed outcomes of nephropathic cystinosis
By acting on the central nervous system (CNS), GLP-1s specifically activate receptors in key brain regions, like the hypothalamus, to regulate energy balance
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Structure and mechanism of bloodbrain-barrier lipid transporter MFSD2A