Cost and equitable access are ongoing challenges
TL;DR There is no FDA-approved TB-500 dosing protocol
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Benefits Carnitine has several benefits, including supplying energy from fat stores, promoting weight loss due to its role in fatty acid oxidation, and seems to help sparing amino acid use during exercise
Daily oral doses of high levels (~100 mg l-carnitine/kg body weight) of this compound are routinely employed in the treatment of organic acidemias and primary carnitine uptake deficiency (OMIM212140) and less frequently in the treatment of multiple other IEMs including, but not limited to, urea cycle defects, fatty acid oxidation disorders, mitochondrial disease, maple syrup urine disease (OMIM248600), and lysinuric protein intolerance (OMIM222700) (Mori et al
Belln T, Lerma V, Gonzlez-Valle O, Gonzlez Herrada C, De Abajo FJ