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The most clinically advanced approach is that taken by DIOSynVax (Digitally Immune Optimised Synthetic Vaccines), who have partnered with PharmaJet for a first-in-human needle-free intradermal vaccine pEVAC-PS encoding their synthetic antigen T2_17 based on coronavirus RBD sequences (Table 3) [152]

This can enhance immune function, improve the gut barrier, and stimulate beneficial microorganisms, potentially preventing disease and oxidative stress

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After six visits and a negative gastrointestinal workup, an astute resident finally asked about menstrual timing and referred her to gynecology, leading to an endometriosis diagnosis