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Do not freeze or expose to extreme heat

Furthermore, PKM2 activation contributes to the intracellular accumulation of succinate, a signaling metabolite that stabilizes HIF-1 and promotes interleukin-1 beta (IL-1) production during inflammatory responses (Tannahill et al., 2013)

The identity of NFT derivatives and/or reactive oxygen species interacting with the Nrf2-Keap1 complex were not identified in the course of the present work, but will be investigated in future studies

mTORC1/2 inhibition preserves ovarian function and fertility during genotoxic chemotherapy

Theres no need for surgery or harsh medications

Notably, several studies have documented hepatomegaly at elevated doses, including those by Pan et al