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35 As discussed earlier, trauma, coupled with an associated genotype, can damage keratinocytes, leading to the expression of IFN and TNF, activation of dendritic cells, and production of IL-23

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See the red line in the graph below: As BAC slowly rises and is under .055: The drinker experiences mild stimulating effects such as increased heart rate, increased energy, self-confidence, sociability, and a feeling of wellbeing or "euphoria." This is the Buzz Zone